About 90% of all malaria deaths in the world today occur in Africa south of the Sahara. This is because the majority of infections in Africa are caused by Plasmodium falciparum, the most dangerous of the four human malaria parasites. It is also because the most effective malaria vector - the mosquito Anopheles gambiae - is the most widespread in Africa and the most difficult to control. An estimated one million people in Africa die from malaria each year and most of these are children under 5 years old.
There are three principal ways in which malaria can contribute to death in young children:
In addition, repeated malaria infections make young children more susceptible to other common childhood illnesses, such as diarrhea and respiratory infections, and thus contribute indirectly to mortality.The consensus view of recent studies and reviews is that malaria causes at least 20% of all deaths in children under 5 years of age in Africa. Children who survive malaria may suffer long-term consequences of the infection. Repeated episodes of fever and illness reduce appetite and restrict play, social interaction, and educational opportunities, thereby contributing to poor development. An estimated 2% of children who recover from malaria infections affecting the brain (cerebral malaria) suffer from learning impairments and disabilities due to brain damage, including epilepsy and spasticity. Malaria affects the lives of almost all people living in the area of Africa defined by the southern fringes of the Sahara Desert in the north, and a latitude of about 28° in the south.
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